Source:
E.Coli
Catalog No.
ENZ-301
Description: Full-length recombinant human neutrophil pro-collagenase (MMP-8), latent form.
Recombinant Human MMP-8 produced in E.Coli is a single, non-glycosylated, polypeptide chain having a molecular mass of 75kDa.
Recombinant MMP-8 is purified by proprietary chromatographic techniques.
Physical Appearance: Sterile Filtered clear solution.
Formulation: The protein Solution (100 ug/ml, 0.1 ml) in 0.05M Tris-HCl buffer, pH 7.5, containing 0.2M NaCl, 5mM CaCl2, 20然 ZnSO4 and 0.1% BSA.
Stability:
Recombinant MMP-8 although stable at 140C for 1 week, should be stored desiccated below -180C.
Please avoid freeze-thaw cycles.
Purity: Greater than 90% as determined by SDS-PAGE. Unit definition: One unit of collagenolytic activity is defined as the cleavage of 1ug of collagen per minute.
Biological Activity: ProSpec旧 Recombinant MMP-8 biological activity was found to be 100 units/ml after activation with APMA by solution assay method (10U=100 assays).
Applications: Used as a standard for analyzing mammalian collagenase activity.
Usage: Prospec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Gene:
Name:MMP8
Synonyms:CLG1
Neutrophil collagenase precursor (EC 3.4.24.34)
(Matrixmetalloproteinase-8)
(MMP-8)
(PMNL collagenase)
(PMNL-CL).
Belongs to the peptidase M10A family.
Domains:
•IPR002477 Peptidoglycan-binding domain 1
•IPR001818 Peptidase M10A and M12B, matrixin and adamalysin
•IPR000585 Hemopexin
•Recombinant Human Matrix Metalloproteinase-13
•Recombinant Human Matrix Metalloproteinase-3
