Source:
E.Coli
Catalog No.
PRO-381
Description : L-Selectin belongs to a family of divalent cation-dependent carbohydrate-binding glycoproteins or adhesion molecules. Lselectin is expressed constitutively on lymphocytes, monocytes and granulocytes and interacts specifically with carbohydrate groups on activated endothelial cells. L-Selectin may be shed by proteolytic cleavage and circulating levels in biological fluids may be used as an indicator of various pathological conditions.
Recombinant Human L-Selectin is expressed in E. coli containing 294 amino acids 39-332 fused to an amino terminal hexahistidine tag. Physical Appearance: Sterile Filtered clear soultion.
Formulation: Recombinant LSel is supplied in 1x Laemmli Buffer (25mM Tris-HCl pH6.8, 50mM DTT, 1%(w/v) SDS, 0.1%(w/v) Bromophenol Blue and 2.5% Glycerol).
Stability: Store at 4蚓 if entire vial will be used within 1-2 weeks. Store, frozen at -20蚓 for longer periods of time.
Please avoid freeze-thaw cycles.
Applications:
Recombinant Human L-Selectin can be used directly as a positive control in Western blotting, ELISA, immunoprecipitation and other immunological experiments.
The biological activity of this product has not yet been tested.
Purity:
Greater than 95% (SDS-PAGE). Single band on Western Blot.
Usage: Prospec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Gene:
Name:SELL
Synonyms:LNHR, LYAM1
L-selectin precursor (Lymph node homing receptor)
(Leukocyte adhesionmolecule 1)
(LAM-1)
(Leukocyte surface antigen Leu-8)
(TQ1)
(gp90-MEL)
(Leukocyte-endothelial cell adhesion molecule 1)
(LECAM1)
(CD62Lantigen).
Belongs to the selectin/LECAM family.
Domains:
•IPR001304 C-type lectin
•IPR013032 EGF-like region
•IPR006209 EGF-like
•IPR000436 Sushi/SCR/CCP
•Recombinant Human E-Selectin
•Recombinant Human P-Selectin
