檔案名稱:rp-1/rHuHEP1.html

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Recombinant Human Heparanase-1

Gene:

Name:HPSE
Synonyms:HEP, HPA, HPA1, HPR1, HPSE1, HSE1

Protein synonyms/aliases:

Heparanase precursor (EC 3.2.-.-)
    (Heparanase-1)
    (Hpa1)
    (Endo-glucoronidase)

Precursor's functional components:

Heparanase 8 kDa subunit
Heparanase 50 kDasubunit .

Protein Family:

Belongs to the glycosyl hydrolase 79 family.

Protein Domains:


Domains:
IPR005199   Glycoside hydrolase family 79, N-terminal

Protein links:

Recombinant Human Heparanase-1 protein domain

Recombinant Human Heparanase-1 protein family


Precursor- Protein structure and amino acid sequence:


Latest Publications:

1. [Heparanase: target for cancer metastatic therapy]
Yao Xue Xue Bao 2005 Oct;40(10):871-5
2. COX-2 induction by heparanase in the progression of breast cancer.
Int J Mol Med 2006 Feb;17(2):221-8
3. Elevated serum heparanase-1 levels in patients with pancreatic carcinoma are associated with poor survival.
Cancer 2006 Feb 1;106(3):532-40
4. Role of endothelial heparanase in delayed-type hypersensitivity.
Blood 2005 Dec 29;
5. [Inhibitory Effect of Silencing Heparanase Expression with Antisense Oligodeoxynucleotide on Invasive Capability of Human Esophageal Squamous Cancer Cell Line TE-13.]
Ai Zheng 2005 Dec;24(12):1431-5
6. [Effect of Exogenous Expression of Heparanase Gene on Invasive Ability of Colorectal Cancer Cell Line HT29.]
Ai Zheng 2005 Dec;24(12):1427-30

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中華民國95年06月06日更新