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Recombinant Hepatitis脷 Virus Core?1-144 a.a.)

Certificate of Analysis and Data Sheet

Source:
E.coli

Catalog No.
HBV-270

Product Description:

E.coli derived recombinant. The protein contains the HBV core immunodominant region.

Physical appearance:

Sterile Filtered colourless liquid formulation

Purification Metod:

Purified by proprietary chromatographic technique.

Purity:

Protein is >90% pure as determined by 10% PAGE (coomassie staining).

Formulation:

1mg/ml in 10mM Tris-HCl pH8.0, 50mM NaCl, 1mM EDTA and 50% glycerol.

Storage:

Protein is shipped at ambient temperature. Upon arrival, Store at -200C.

Stability:

Five years frozen. One month in solution at room temperature.

Specificity:

Immunoreactive with sera HBV-infected individuals.

Applications:

Antigen in ELISA and Western blots, excellent antigen for detection of HBV with minimal specificity problems.

Usage:

This material is offered by ProSpec-TechnoGene for research, laboratory or further evaluation purposes.


Gene:

Name:C
Synonyms:c, core

Protein synonyms/aliases:

HBcAg (Core protein).

Protein Family:


Protein Domains:


Domains:
IPR002006   Hepatitis core antigen

Protein links:

Recombinant Hepatitis脷 Virus Core?1-144 a.a.) protein domain

Recombinant Hepatitis脷 Virus Core?1-144 a.a.) protein family


Precursor- Protein structure and amino acid sequence:


Latest Publications:

1. Detection of HBsAg, HBcAg, and HBV DNA in ovarian tissues from patients with HBV infection.
World J Gastroenterol 2005 Sep 21;11(35):5565-7
2. Effects of IL-12 and IL-18 on HBcAg-specific cytokine production by CD4 T lymphocytes of children with chronic hepatitis B infection.
Antiviral Res 2005 Apr;66(1):23-7
3. [Presentation of HIV epitopes by HBcAg]
Vestn Ross Akad Med Nauk 2005;(1):37-40
4. Exposure of RNA templates and encapsidation of spliced viral RNA are influenced by the arginine-rich domain of human hepatitis B virus core antigen (HBcAg 165-173).
J Virol 2005 Feb;79(3):1871-87
5. [Relevancy between liver injury, serum HBV-DNA, and intrahepatic HBcAg in young male chronic HBV carriers]
Korean J Gastroenterol 2004 Aug;44(2):84-92
6. [The expression of HBsAg and HBcAg in the liver tissues of the patients with chronic hepatitis B before and after the treatment with arabinosyladenine]
Zhonghua Gan Zang Bing Za Zhi 2004 Aug;12(8):452

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中華民國95年06月06日更新