Certificate of Analysis and Data Sheet

Source:

Catalog No.
HOR-254

Description :

Human Oxytocin(Pitocin/Syntocinon) stimulates uterine smooth muscle contractions indirectly and stimulates the mammary glands to increase lactation without increasing the production of milk. Human Oxytocin is purified by proprietary chromatographic techniques.

Physical Appearance:

Sterile Filtered White lyophilized (freeze-dried) powder.

Formulation:

Lyophilized from a concentrated (1 mg/ml) solution in water containing no additives.

Solubility:

It is recommended to reconstitute the lyophilized Oxytocin in sterile 18MΩ-cm H2O not less than 100ug/ml, which can then be further diluted to other aqueous solutions.

Stability:

Lyophilized Oxytocin although stable at room temperature for 3 weeks, should be stored desiccated below -18 C. Upon reconstitution Oxytocin should be stored at 4 C between 2-7 days and for future use below -18 C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Please avoid freeze-thaw cycles.

Purity:

Greater than 98.0% as determined by:
(a) Analysis by RP-HPLC.
(b) Mass Spectral Anaylsis (MALDI-TOF exhibits correct Mw)

Amino acid sequence:

Cys-Tyr-Ile-Gln-Asn-Cys-Pro-Leu-Gly-NH2.

Usage:

Prospec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

Gene:

Name:OXT
Synonyms:OT

Protein synonyms/aliases:

Oxytocin-neurophysin 1 precursor (OT-NPI)

Precursor's functional components:

Oxytocin(Ocytocin)
Neurophysin 1 .

Protein Family:

Belongs to the vasopressin/oxytocin family.

Protein Domains:

Domains:
•IPR000981   Neurohypophysial hormone

Protein links:

Precursor- Protein structure and amino acid sequence:

Latest Publications:

1. The chemistry of child neglect: do oxytocin and vasopressin mediate the effects of early experience?
Proc Natl Acad Sci U S A 2005 Dec 20;102(51):18247-8
2. Up-regulation of rat myometrial phospholipases C{beta}1 and C{beta}3 correlates with increased term sensitivity to carbachol and oxytocin.
J Endocrinol 2005 Nov;187(2):197-204
3. Pervasive social deficits, but normal parturition, in oxytocin receptor-deficient mice.
Proc Natl Acad Sci U S A 2005 Nov 1;102(44):16096-101
4. Introduction of a cis-prolyl mimic in position 7 of the peptide hormone oxytocin does not result in antagonistic activity.
J Med Chem 2005 Oct 20;48(21):6553-62
5. Vasopressin/oxytocin and aggression.
Novartis Found Symp 2005;268:190-8; discussion 198-200, 242-53
6. Effects of long-term treatment with oxytocin in chronic constipation; a double blind, placebo-controlled pilot trial.
Neurogastroenterol Motil 2005 Oct;17(5):697-704

採購找生工，預算最輕鬆。

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中華民國95年06月06日更新